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Medicine and Dentistry >
Dentistry, Oral Surgery and Medicine
Indian Journal of Immunology and Respiratory Medicine
Editor in chief:Dr. Sankalp Yadav
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Importance Of Community Meetings In Control Of Tuberculosis
Author:Sunil Kumar, Sankalp Yadav
Volume: 1 | Issue no: 3-2016 | Pagination: 76-77
Tuberculosis (TB) is fast emerging as the major public health concern, especially in the developing countries, in terms of morbidity and mortality[1-4] . The grave consequences of this disease is the emergence of the drug resistant TB (DR-TB?s) like the Multidrug resistant (MDR) and extensively drug resistant TB (XDR-TB) [2,5,6] . The most distressing fact about drug resistant TB is detection of Multi drug resistance among the primary cases, i.e. patients diagnosed for the first time with the strain of Mycobacterium tuberculosis that is resistant to Rifampicin and other first line anti tubercular drugs
Mycoplasma Pneumonia Associated With Severe Cold Autoimmune Haemolytic Anemia
Author:S. Pirasath, G. Selvaratnam
Volume: 1 | Issue no: 3-2016 | Pagination: 74-75
We report a case of cold autoimmune hemolytic anemia secondary to Mycoplasma pneumoniae in an 18 years old lactating mother presenting with respiratory symptoms and severe anemia. Her direct agglutination assay was strongly positive with marked IgG and C3d titre and cold agglutination test was high titre with anti I specificity. Mycoplasma antibody titre by complement fixation was 1280. She was treated with Azithromycin and Predisolone for pneumonia and packed red cells for anemia.
Chemical Pneumonitis Following Diesel Oil Siphonage: A Case Report And Review Of Literature
Author:Sujeet Raina, Ansari Mohd Shoeb, Rajesh Sharma, Amandeep Raghuvanshi
Volume: 1 | Issue no: 3-2016 | Pagination: 70-73
Reports of diesel aspiration followed by chemical pneumonitis and its management have rarely been published. Details of clinical features, imaging findings, appropriate management and outcome of this condition are available in literature in the form of individual case reports. We present a case of diesel aspiration induced chemical pneumonitis that was successfully treated in our medicine ward.
Blunt Thoracic Trauma Treatment Outcomes- A Small Center Experience
Author:Shegu Gilbert, Devender Singh, Rahul Satheesan, Gowtham Sundaram Venkatesan, Mrinalini Singh
Volume: 1 | Issue no: 3-2016 | Pagination: 67-69
Background: Blunt injury to the chest has a high risk of morbidity and mortality. Road traffic accidents are the major cause of blunt injury to the chest. We aimed to analyze the demographics, mode of injury, radiological findings, injury scores, length of stay and mortality of patients with chest trauma admitted to the cardiothoracic unit at our tertiary care hospital. Materials and Methods: Retrospective data analysis of 53 patients admitted to the cardiothoracic unit from January 2016 to March 2016 was under taken. All patients with chest injury were included in the study. Patients with major head trauma were excluded. Statistical analysis was done. Variables were expressed as mean ± standard deviation and percentage. Results: Mean age of patients were 45.5±15 years. Only fifteen percent of patients were females. Motor vehicle accidents was the major cause of blunt injury chest (75.7%). Incidence of extra thoracic injuries were 75.5%. Most common injury were rib fractures (85%). 51.5% of patients required intercostal drainage. Length of hospital stay was 9.2±5.6 days. Average injury severity score (ISS) was 30.63±16.79. Conclusions: Majority of patients with blunt injury to the chest require simple techniques of management like intercostal drainage (ICD) which is lifesaving in the emergent setting. ICD and serial radiological monitoring and observation with supportive treatment like analgesia, ventilator support and adequate chest physiotherapy is sufficient in most of the patients. Multi-disciplinary approach with active involvement of other specialties and physiotherapy improves the outcomes for trauma patients
Clinico-Radiological Profile And Diagnostic Yield Of Various Procedures In Analysis Of Tubercular Pleural Effusion
Author:Chaina Ram Choudhary, Laxman Kumar Soni, Shrawan Ram, Gopal Purohit, Sunil Vyas, Priyanka Soni
Volume: 1 | Issue no: 3-2016 | Pagination: 63-66
Background: Tuberculosis is the leading cause of pleural effusion in developing countries. Early diagnosis and treatment of this condition is imperative as it is associated with high morbidity and mortality. Pleural biopsy has been considered the gold standard in diagnosis of TPE but it is invasive, so that pleural fluid markers of TPE have been extensively evaluated as an alternative to pleural biopsy. Methods: Prospective study included 100 cases with Detailed clinical history, Radiological examination and NAATs i.e. MTB DNA PCR with other conventional diagnostic techniques like pleural fluid biochemistry, ADA, cytology and culture for mycobacterium tuberculosis was carried out in all patients. Results: Out of total 100 cases, 09% cases were sputum positive for AFB, 3% pleural fluid positive for AFB, 28% were culture positive, 74% were DNA PCR positive, and 85% cases had ADA >40 units/liter, 87% cases had a LN Ratio greater than 0.75. Sensitivity, specificity, PPV & NPV of PCR for MTB was observed 92.86%, 33.33%, 35.13% & 92.30% respectively (p<0.01). ATT response was observed in 78% cases in 2 weeks, 98% cases in 4 weeks and 100% cases at the end of 6 weeks. Conclusions: Delay in diagnosis of TPE leads to sequelae as well as spread of infection to other organs. More than one diagnostic procedure is often needed for confirmation of TPE. PCR targeting IS6110 is the simple, rapid and highly sensitive test used in the early diagnosis of TPE
A Study On The Levels Of Ige As A Biomarker In The Management Of Bronchial Asthma Patients
Author:Kavitha Devi M, Yuvarajan S, Vickram Reddy, Kalaikovan B
Volume: 1 | Issue no: 3-2016 | Pagination: 58-62
Background: IgE is a major contributing factor for the development of bronchial hyper responsiveness in asthmatics. Serum IgE levels also shows association with degree of airflow obstruction. Therefore, a study was undertaken to estimate the serum IgE level in bronchial asthma patients, and to correlate the severity of airway obstruction with serum IgE level in bronchial asthma patients. A total of 75 cases in the age group of 21-60 years, of Tertiary care Hospital, Madagadipet, Puducherry-India was included in the study. Spirometry with reversibility testing was done in all cases. Serum IgE level was estimated using Quantia IgE, which is a turbid metric immunoassay. Patients with bronchial asthma had elevated serum IgE, which increased with increase in the severity of airflow obstruction and it was found to be statistically significant (p <0.05). It was concluded that Serum IgE level increases as the severity of airflow obstruction increases. It helps to classify the Bronchial asthma patients based on IgE and to guide anti IgE therapy for the patients with difficult to treat allergic asthma and to assess its response.
A Child With Primary Spontaneous Mediastinal Emphysema ? A Rare Presentation Of A Self-Limiting Disease
Author:Devender Singh, Shegu Gilbert, Rajendran K, Mrinalini Singh
Volume: 1 | Issue no: 3-2016 | Pagination: 55-57
Spontaneous mediastinal emphysema is a rare occurrence in children while it is relatively more common in adolescents. It leads to subcutaneous emphysema, pneumomediastinum and pneumopericardium. We report a nine year old boy, a non-asthmatic who presented with fever and incessant cough for three days. He developed sudden onset chest pain and crepitant swelling of the chest-wall, neck and face. He was observed in the intensive care unit. Cardiopulmonary monitoring was done. Antibiotic, nebulization and oxygen supplementation were given. Recovery was uneventful. We discuss the clinical features, aetiopathogenesis, diagnosis and management of this rare condition.
The Use Of Ultrasonography In Pregnancy In The Current Pandemic Of Zika Virus
Author:Sankalp Yadav, Gautam Rawal
Volume: 1 | Issue no: 3-2016 | Pagination: 53-54
The world is facing a pandemic in progress due to an emerging arbovirus of the Flaviviridae family called Zika virus (ZIKV) . ZIKV is a mosquito-borne flavivirus[2,3] . The paucity of literature and nonavailability of clear guidelines has led to panic, especially among the pregnant women. The current situation in some of the countries is so grave that the health advisors have even asked to postpone the pregnancy to avoid the cases of fetal anomalies. And the fetal anomaly that has raised alarms worldwide is the microcephaly
The Ards Kigali Definition: Do We Need A New Definition For Low-Income Countries?
Author:Gautam Rawal, Sankalp Yadav, Raj Kumar
Volume: 1 | Issue no: 2-2016 | Pagination: 51-52
Acute respiratory distress syndrome (ARDS) has always been the center of research during the past decades due to its high mortality and morbidity. The ARDS definition of the Berlin conference has received both appreciation and criticism and has now travelled a long journey to the Kigali city of Rwanda, to be modified. This Kigali modification of ARDS definition allows the identification of ARDS not only in rich or middle-income countries, but also in the low-income countries or in the healthcare facilities with very limited resources. In a developing country like India, there are still a large number of healthcare facilities which lack the proper resources. Further research on this modified definition is needed for its proper validation and reliability and consequent widespread use
Spontaneous Pneumomediastinum And Subcutaneous Emphysema: An Unusual Presentation Of H1n1 Influenza In Adult. Case Report With A Brief Literature Review
Author:Naorem Dhaneshwor Singh, Jaswinder Kaur, Desh Deepak, Lobzang Dawa
Volume: 1 | Issue no: 2-2016 | Pagination: 47-50
Swine flu is a highly contagious acute respiratory disease caused by a subtype of influenza-A virus. After the 2009 H1N1 virus pandemia the strain has caused multiple localized outbreaks in various part of the world. The disease presents typically with fever, cough, sore throat, chills, headache, rhinorrhea, dyspnea, myalgia, arthralgia, fatigue, vomiting, and diarrhea. A varied clinical spectrum of its presentation ranging from non-febrile, mild upper respiratory tract illness or febrile influenza-like illness to severe or even fatal complications, including rapidly progressive pneumonia, septic shock and multiorgan failure has been described.  Other severe complications include secondary invasive bacterial infections, myocarditis, encephalitis and worsening of underlying chronic disease condition like asthma, heart failure and chronic obstructive pulmonary disease.  Spontaneous pneumomediastinum (SPM) is a rare complication of H1N1 swine-flu infection, occurring mostly in children with a predisposing comorbidity like asthma. Extensive search of previous publications revealed only a single case of its occurrence in adult, who was undergoing treatment for moderate asthma
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